Overview

Angular cheilitis (perlèche) may be a chronic inflammatory condition of the corners of the mouth. Usually related to a fungal (Candidal) or bacterial (Staphylococcal) infection, those affected can also have thrush (oral candidiasis). The areas are generally slightly painful. The condition can last from days to months, depending upon whether or not the affected person seeks treatment.

Who's at risk?

Angular cheilitis may affect people of all ages. Chronic pooling of saliva encourages fungal and bacterial growth, and patients who are immunocompromised, have undergone head and neck radiation, or have DM also are susceptible to this condition.

Patients who are predisposed to the present condition also may have problems with:

Ø     Iron deficiency

Ø    Vitamin B12 deficiency

Ø     Folate deficiency

Ø     Drooping of the corners of the mouth caused by dentures that do not adequately support the facial musculature

Signs and Symptoms

Angular cheilitis are often found within the corners of the mouth. A patient with angular cheilitis may notice:

Ø  Cracking and fissuring of the corners of the mouth, with redness

Ø  Ulceration

Ø  Drainage of pus

Ø  Tissue softness and tenderness

Self-Care Guidelines

Dentures may act as reservoirs of infection. To prevent angular cheilitis, try soaking dentures overnight during a solution made from 10 parts water to 1 part household bleach. For metal dentures which will become discolored by bleach, the utilization of a benzoate of soda or chlorhexidine mouth rinse may be a good option.

When to Seek Medical Care

If persistent lip irritation, painful cracking, or fissuring at the corners of the mouth is present, seek evaluation from your medical care provider or dermatologist.

Treatments Your Physician May Prescribe

Treatment of angular cheilitis is typically undertaken with topical antifungals like nystatin, clotrimazole, or econazole. Combinations of a topical antifungal and a topical steroid – like Mycostatin® and triamcinolone or iodoquinol and hydrocortisone – can also be prescribed. In persistent cases, oral antifungals could also be wont to treat the condition.

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