Overview

Antiphospholipid syndrome occurs when your system mistakenly creates antibodies that make your blood far more likely to clot.

This can cause dangerous blood clots within the legs, kidneys, lungs and brain. In pregnant women, antiphospholipid syndrome can also end in miscarriage and stillbirth.

There's no cure for antiphospholipid syndrome, but medications can reduce your risk of blood clots.

Symptoms

Signs and symptoms of antiphospholipid syndrome can include:

Ø     Blood clots in your legs (DVT). Signs of a DVT include pain, swelling and redness. These clots can visit your lungs (pulmonary embolism).

Ø     Repeated miscarriages or stillbirths. Other complications of pregnancy include dangerously high vital sign (preeclampsia) and premature delivery.

Ø     Stroke. A stroke can occur during a youth who has antiphospholipid syndrome but no known risk factors for cardiovascular diseases.

Ø     Transient ischemic attack (TIA). almost like a stroke, a TIA usually lasts only a couple of minutes and causes no permanent damage.

Ø     Rash. Some people develop a red rash with a lacy, net-like pattern.

Less common signs and symptoms include:

Ø     Neurological symptoms. Chronic headaches, including migraines; dementia and seizures are possible when a grume blocks blood flow to parts of your brain.

Ø     Cardiovascular disease. Antiphospholipid syndrome can damage heart valves.

Ø     Bleeding. Some people have a decrease in blood cells needed for clotting. this will cause episodes of bleeding, particularly from your nose and gums. you'll also bleed into your skin, which can appear as patches of small red spots.

Causes

Antiphospholipid syndrome occurs when your system mistakenly produces antibodies that make your blood far more likely to clot. Antibodies normally protect the body against invaders, like viruses and bacteria.

Antiphospholipid syndrome are often caused by an underlying condition, like an autoimmune disease , infection or certain medications. you furthermore may can develop the syndrome without an underlying cause.

Risk factors

Risk factors for antiphospholipid syndrome include:

Ø     Your sex. This condition is far more common in women than in men.

Ø     Immune system disorders. Having another autoimmune condition, like lupus or Sjogren's syndrome, increases your risk of antiphospholipid syndrome.

Ø     Infections. This condition is more common in people that have certain infections, like syphilis, HIV/AIDS, hepatitis C or Lyme disease.

Ø     Medications. Certain medications are linked to antiphospholipid syndrome. They include hydralazine for top vital sign , the guts rhythm-regulating medication quinidine, the anti-seizure medication phenytoin (Dilantin) and therefore the antibiotic amoxicillin.

Ø     Family history. This condition sometimes runs in families.

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